AAV-2 CMV Expression System - 1 kit

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    • Complete Expression System contains packaging plasmids, expression vector and GFP control vector for packaging of recombinant AAV serotype 2
    • pHelper plasmid contains required E2A, E4, and VA RNA adenoviral genes; eliminates the need for a helper adenovirus
    • Cloning capacity of expression vector = 3 kb

    The AAV Helper Free System produces recombinant AAV containing your gene of interest without the need to use a helper adenovirus. The adenoviral genes required for proper AAV packaging are provided in the pHelper plasmid (E2A, E4 and VA RNA) or in the 293 packaging cells.

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    5. Robert, M.A. et al. (2018). Gene Transfer of ZMapp Antibodies Mediated by Recombinant Adeno-Associated Virus Protects Against Ebola Infections. Hum Gene Ther. 29(4):452-466. doi: 10.1089/hum.2017.101.